I speculate that one equivalent is that city people tend to be more accustomed to manipulation and generally interacting with other humans, especially strangers. Your average rural person probably never meets strangers in a typical day. So if you're a rural person in the city it'd be unbelievably overwhelming, forcing you into a defensive posture.
It also marks you as a rube. You might be perfectly intelligent and well educated but you're vulnerable to being taken advantage of.
City people may come off as cold, manipulative, scary because of it. Unscrupulous people can take advantage of you more easily. You're a mark.
I only just heard this the first time recently and it's got some stickiness to it! Definitely a song people will recognize a couple decades from now. Centuries, maybe not.
