Great pick. This track is transcendent.
If I had to choose one song, it would probably have to be Undertale from Undertale. The acoustic guitar brought me to tears. Honorable mentions to Rith Essa Mime from Jet Force Gemini, Stone Tower Temple from Majora's Mask, Smiles and Tears from Earthbound, Fear the Dark from Aquaria, and Ocean Planet Aquanid from Bomberman 64: The Second Attack.
I wish Want You Gone was more popular, because it's genuinely a better song and plays the relationship double entendre so well.