They would immediately form a treaty to avoid conflict, even if it cost lives.
If anyone formed their own independent rebellion to stop the pirates, Starfleet would poison the planets their bases were on to avoid breaking that treaty
Poor worf. Doesn't even know he has a child then BAM, here's your child, the mother is dead and she taught your kid to not understand or value anything you valued. Not to mention the trauma of his mate being murdered. If that wasn't enough, people constantly pick on him for not pulling up his bootstraps and being the best parent ever.