The workings of any particular variant are largely irrelevant.

In effect it still promotes the idea that rather than eat better and live healthier that your problems should be solved with a pill or shot.

Edit: Since diet and exercise are so unpopular here, I've yet to see anyone explain how it is that the average obesity rate in the USA has grown so significantly over the past century in anything beyond a ambiguous 'medical condition' or 'genetics'.

The makeup of the human species hasn't so dramatically evolved over the course of a few generations, that's simply not how evolution works, but somehow despite supposedly nobody overeating and everyone getting plenty of good exercise we've gotten to a point where Americans are globally stereotyped as being big fat slobs.