The meme isn't really referencing the actor, but rather the character. Eliot might not be a woman, but the character is. When cis guys play female characters, we still refer to the character as female. I don't see why it should be any different when a trans guy plays a female character.
Maybe I missed that bit of the news cycle but when was Kamala acting like she didn't want a debate? I remember her being hesitant about the rules Trump was demanding at first, but that's about it.
My response, when my mom showed my first partner naked baby pictures was to nudge my partner and say "don't worry, I'll send you some more recent ones.
My mom super didn't appreciate the joke, but she never pulled out baby pictures for future partners.
No shot of winning the popular vote. But between the electoral college and his rampant election rigging, this election is far from certain.