Something else that I think is an important part of this discussion, especially in regard to family members, is long-term medical issues.

There are a lot of medical conditions that are gender-specific, especially with aging. For one example, an FTM transitioned individual will likely still experience menopause. That is the actual menopause condition, not just similar symptoms. An MTF individual may experience menopause-like symptoms due to complications with estrogen therapy. Evidence also suggests that transgender women have the same risk of cardiovascular issues as the general male population:

Evidence from several studies suggests that cardiovascular risk is unchanged among transgender men using testosterone compared with non-transgender women. Evidence in transgender women is less clear. Some studies have found increased morbidity and mortality from myocardial infarction and stroke compared with non-transgender men, however these studies did not adjust for a number of risk factors including tobacco use, obesity, and diabetes.

https://transcare.ucsf.edu/guidelines/cardiovascular

Functionally, if you were born male then your cardiovascular system is still the same. However, as noted in this study there is not a large body of research on this specific subject and there are many complicating factors, so the above conclusion is tentative. Hopefully we will get more research and better statistics, but long-term studies are slow.

Unfortunately these issues don't go away just because you look and feel different now - we just don't have the technology to make real changes to your genetics, not yet anyway.

If you are transitioning, obviously you're having a lot of conversations with your medical team about all of this. I would encourage you to please also discuss it with your family. They won't have all the specifics that you do about the side effects unless you talk to them about it.

If your family is disassociating with you because of your transition - first of all I am very, very sorry and I hope you either have or find some new family. Please please make an effort to have a person in your life (other than a medical professional) who you can trust enough to discuss your medical situation with. I know it's very personal, but like... everybody needs care and support, and to get that you need other people with patience and understanding, and to have understanding you need communication. Talk to people who care about you, and give them at least some of the specifics. And really... you need that care and support from someone directly involved in your personal life, not just the trans community on the internet. You need someone who can look at you and see that you are struggling.