Multiple CalDAV calendars synced to email aliases for a single email account?

Has anyone managed to get multiple CalDAV calendars (e.g. personal and work) to send out event invite emails using corresponding email aliases from the same email account?

I have multiple domains and aliases set up with a single email account through an email provider, but I'm just now trying to figure out how to separate the calendar into personal and work.

EDIT: I managed to get it set up and working with nextcloud! So yes, this is possible